Seborrheic keratosis-like changes in epidermal inclusion cyst: An unusual feature in a usual entity

Seborrheic keratosis-like changes in epidermal inclusion cyst: An unusual feature in a usual entity

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A 58-year-old male presented with an asymptomatic, slowly growing, cystic and mobile Reloading swelling on the left leg calf of 6 months duration.Fine-needle aspiration cytology was suggestive of epidermal inclusion cyst.Histopathological examination revealed seborrheic keratosis-like changes in the cyst Rx - Antibiotics wall comprising of marked acanthosis, papillomatosis, pseudohorn cysts, squamous eddies, and clumps of keratohyalin granules.This is a very rare variant of epidermal inclusion cyst, possibly induced by infection with human papillomavirus.